герпес на ладони

Тербинафин suppresses synthesis эргостерола, making a membrane of mushrooms, due to action on enzyme сквален-эпоксидазу, supervising formation{education} of one of early predecessors эргостерола. In result the maintenance{contents} эргостерола is reduced, but the maintenance{contents} сквалена raises. Фунгистатический the effect тербинафина is connected to oppression of synthesis of a membrane because of shortage эргостерола. Besides тербинафин shows expressed фунгицидный effect (at least in vitro) which exact mechanism is not found out. The destruction of mushrooms can come as a result of full oppression of synthesis эргостерола, but most likely, it occurs due to accumulation of plenties сквалена, mushrooms destroying a membrane. It is possible also, that frustration of synthesis эргостерола results in infringement of synthesis of chitin, a basis of a cellular wall плесневых mushrooms. Фунгицидный the effect arises at smaller concentration тербинафина, than it is required for full oppression of synthesis эргостерола. Подробнее...

The mycosis stop (palms) is necessary for differentiating from дисгидротической экземы, псориаза, пустулезного бактерида Andrews, кератодермии, and also at localization of the centers: on shins - from knotty васкулита, папулонекротического a tuberculosis, the limited neurodermatitis; on a leather{skin} of a trunk - from псориаза, superficial and chronic трихофитии, инфильтративной and инфильтративно-нагноительной forms зооантропонозной трихофитии, паховой эпидермофитии; on the person - from red волчанки. Подробнее...