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Гистоплазмоз it is caused диморфным barmy грибком Histoplasma capsulatum and in Holland it is sometimes observed at natives of Surinam and Indonesia. Гистоплазмоз also it can be observed at patients who travelled on the USA, mainly in states Mississipi and Ohio. The primary infection can proceed бессимптомно or be shown as a pneumonia. Just as at a tuberculosis, the infection got at young age, can become in more advanced age demonstrating owing to decrease{reduction} in immunity. Гистоплазмоз at patients with AIDS it is shown more often диссеминированной by an infection with a fever, the general{common} indisposition, гепатоспленомегалией, defeat of a leather{skin} and mucous and нодулярными легочными инфильтратами. The diagnosis put by results of crops of blood or биопсии the struck bodies. Sometimes the diagnosis can be quickly put by direct research аспирата a bone brain if about it is directed brings an attention to the question laboratory. Подробнее...

Кандидемия at patients without гранулоцитопении. This complication is observed mainly at patients of branches of intensive therapy after абдоминальной surgeries, at receiving парентеральное a feed{meal} and after treatment by antibiotics of a wide spectrum. The fever frequently is a unique symptom, and the positive result of crop of blood on Candida frequently is unexpectedness. Taking into account risk of dispersion of the centers, treatment is shown, in our opinion, even at presence only one positive crop of blood [3]. Business is much more difficultly if at the patient of branch of intensive therapy having a constant fever, colonization Candida of respiratory, digestive and urinogenital pathes is observed. That crops of blood frequently become positive only in a late stage, distinction between colonization and инвазивной an infection is difficult to lead{carry out}. Modern молекулярно-biological researches can show, that isolated штамм is identical штамму by which the patient has already been colonized earlier. Is sometimes shown to begin empirical противогрибковое treatment even if it is impossible to define{determine} precisely when this treatment should be started. However the threshold for the beginning противогрибковой therapies at these обстоятельст вах has gone down, as less toxic became accessible фунгостатические means. Подробнее...